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1

Pharmacological treatment options formast cell activation disease

Molderings, Gerhard J., Haenisch, Britta, Brettner, Stefan, Homann, Jürgen, Menzen, Markus, Dumoulin, Franz Ludwig, Panse, Jens, Butterfield, Joseph, Afrin, Lawrence B.

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2016

Language:

english

File:

PDF, 906 KB

english, 2016

2

High-throughput melting-temperature analysis of a monoclonal antibody by differential scanning fluorimetry in the presence of surfactants

Menzen, Tim, Friess, Wolfgang

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 523 KB

english, 2013

3

Novel High-Throughput Assay for Polysorbate Quantification in Biopharmaceutical Products by Using the Fluorescent Dye DiI

Martos, Ariadna, Berger, Michelle, Kranz, Wendelin, Spanopoulou, Anna, Menzen, Tim, Friess, Wolfgang, Wuchner, Klaus, Hawe, Andrea

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.75 MB

english, 2019

4

Exploring Chemical Space for new Substances to stabilize a therapeutic Monoclonal Antibody

Tosstorff, Andreas, Menzen, Tim, Winter, Gerhard

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 3.14 MB

english, 2019

5

EinfluÃ der Eisenbegleiter auf die Aenderung von Festigkeitseigenschaften von normalgeglÃ¼htem weichen Stahl im Blaubruchgebiet

Eilender, Walter, Cornelius, Heinrich, Menzen, Paul

Journal:

Archiv für das Eisenhüttenwesen

Year:

1940

File:

PDF, 978 KB

1940

6

Zum Verhältnis von ästhetischer Theorie und ästhetischer Psychologi

Dr. Karl-Heinz Menzen

Journal:

Berichte zur Wissenschaftsgeschichte

Year:

1981

File:

PDF, 468 KB

1981

7

Numerical density of δ-opioid receptor expressing neurons in the frontal cortex of drug-related fatalities

P Schmidt, C Schmolke, F Mußhoff, M Menzen, C Prohaska, B Madea

Journal:

Forensic Science International

Year:

2000

Language:

english

File:

PDF, 956 KB

english, 2000

8

Numerical density of μ opioidreceptor expressing neurons in the frontal cortex of drug related fatalities

P Schmidt, C Schmolke, F Mußhoff, C Prohaska, M Menzen, B Madea

Journal:

Forensic Science International

Year:

2001

Language:

english

File:

PDF, 923 KB

english, 2001

9

Area-specific increased density of μ-opioid receptor immunoreactive neurons in the cerebral cortex of drug-related fatalities

Peter Schmidt, Cordula Schmolke, Frank Musshoff, Markus Menzen, Cathleen Prohaska, Burkhard Madea

Journal:

Forensic Science International

Year:

2003

Language:

english

File:

PDF, 291 KB

english, 2003

10

The[g92/2]8+state in96Zr

M. L. Stolzenwald, G. Lhersonneau, S. Brant, G. Menzen, K. Sistemich

Journal:

Zeitschrift für Physik A Hadrons and Nuclei

Year:

1987

Language:

english

File:

PDF, 154 KB

english, 1987

11

The decay scheme of the 3-sIsomer of100Nb and the properties of levels in100Mo

G. Menzen, K. Sistemich, G. Lhersonneau, H. Gietz

Journal:

Zeitschrift für Physik A Hadrons and Nuclei

Year:

1987

Language:

english

File:

PDF, 614 KB

english, 1987

12

The nilsson-potential parameters for neutrons at A≃-100 and new deformation values for103Mo and105Mo

T. Seo, H. Lawin, G. Lhersonneau, R. A. Meyer, G. Menzen, K. Sistemich

Journal:

Zeitschrift für Physik A Hadrons and Nuclei

Year:

1985

Language:

english

File:

PDF, 453 KB

english, 1985

13

Magnetic moments of the 21+states in102, 104Mo

G. Menzen, A. Wolf, H. Lawin, G. Lhersonneau, K. Sistemich

Journal:

Zeitschrift für Physik A Hadrons and Nuclei

Year:

1985

Language:

english

File:

PDF, 537 KB

english, 1985

14

Über Gelenkerkrankungen bei Psoriasis

Journal:

Archives of Dermatological Research

Year:

1904

Language:

german

File:

PDF, 1.46 MB

german, 1904

15

Immunhistochemische Untersuchungen zur δ-Opiatrezeptordichte im Kortex Drogentoter Ein Humanmodell chronischer Opiatexposition

P. Schmidt, C. Schmolke, F. Musshoff, M. Menzen, C. Prohaska, B. Madea

Journal:

Year:

2001

Language:

german

File:

PDF, 214 KB

german, 2001

16

cAMP inhibits modulation of airway smooth muscle phenotype via the exchange protein activated by cAMP (Epac) and protein kinase A

Sara S Roscioni, Bart GJ Dekkers, Alwin G Prins, Mark H Menzen, Herman Meurs, Martina Schmidt, Harm Maarsingh

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

17

Protein kinase A and the exchange protein directly activated by cAMP (Epac) modulate phenotype plasticity in human airway smooth muscle

Sara S Roscioni, Alwin G Prins, Carolina RS Elzinga, Mark H Menzen, Bart GJ Dekkers, Andrew J Halayko, Herman Meurs, Harm Maarsingh, Martina Schmidt

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

18

A superconducting magnet for g-factor studies at JOSEF

J.W. Borgs, J. Chatzipetros, H. Lawin, G. Menzen, K. Sistemich, A. Wolf

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1987

Language:

english

File:

PDF, 417 KB

english, 1987

19

Epac as a novel effector of airway smooth muscle relaxation

Sara S. Roscioni, Harm Maarsingh, Carolina R.S. Elzinga, Janke Schuur, Mark Menzen, Andrew J. Halayko, Herman Meurs, Martina Schmidt

Journal:

Journal of Cellular and Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 962 KB

english, 2011

20

Increased arginase activity contributes to airway remodelling in chronic allergic asthma

Maarsingh, H., Dekkers, B. G. J., Zuidhof, A. B., Bos, I. S. T., Menzen, M. H., Klein, T., Flik, G., Zaagsma, J., Meurs, H.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 768 KB

english, 2011

21

Noncanonical WNT-5A signaling regulates TGF- -induced extracellular matrix production by airway smooth muscle cells

Kumawat, K., Menzen, M. H., Bos, I. S. T., Baarsma, H. A., Borger, P., Roth, M., Tamm, M., Halayko, A. J., Simoons, M., Prins, A., Postma, D. S., Schmidt, M., Gosens, R.

Journal:

The FASEB Journal

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

22

PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells

Sara S Roscioni, Loes EM Kistemaker, Mark H Menzen, Carolina RS Elzinga, Reinoud Gosens, Andrew J Halayko, Herman Meurs, Martina Schmidt

Journal:

Respiratory Research

Year:

2009

Language:

english

File:

PDF, 4.42 MB

english, 2009

23

Glycogen synthase kinase-3 (GSK-3) regulates TGF-β 1 -induced differentiation of pulmonary fibroblasts

Baarsma, Hoeke A, Engelbertink, Lilian HJM, van Hees, Lonneke J, Menzen, Mark H, Meurs, Herman, Timens, Wim, Postma, Dirkje S, Kerstjens, Huib AM, Gosens, Reinoud

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

24

Arginase Inhibition Prevents Inflammation and Remodeling in a Guinea Pig Model of Chronic Obstructive Pulmonary Disease

Pera, T., Zuidhof, A. B., Smit, M., Menzen, M. H., Klein, T., Flik, G., Zaagsma, J., Meurs, H., Maarsingh, H.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

25

Temperature-Ramped Studies on the Aggregation, Unfolding, and Interaction of a Therapeutic Monoclonal Antibody

Menzen, Tim, Friess, Wolfgang

Journal:

Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 553 KB

english, 2014

26

l-Thyroxine promotes a proliferative airway smooth muscle phenotype in the presence of TGF-β1

Dekkers, Bart G. J., Naeimi, Saeideh, Bos, I. Sophie T., Menzen, Mark H., Halayko, Andrew J., Hashjin, Goudarz Sadeghi, Meurs, Herman

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2015

Language:

english

File:

PDF, 754 KB

english, 2015

27

-Catenin signaling is required for TGF- 1-induced extracellular matrix production by airway smooth muscle cells

Baarsma, H. A., Menzen, M. H., Halayko, A. J., Meurs, H., Kerstjens, H. A. M., Gosens, R.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2011

Language:

english

File:

PDF, 636 KB

english, 2011

28

Glycogen synthase kinase-3 regulates cigarette smoke extract- and IL-1 -induced cytokine secretion by airway smooth muscle

Baarsma, H. A., Meurs, H., Halayko, A. J., Menzen, M. H., Schmidt, M., Kerstjens, H. A. M., Gosens, R.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

29

Laser-induced breakdown detection of temperature-ramp generated aggregates of therapeutic monoclonal antibody

Menzen, Tim, Friess, Wolfgang, Niessner, Reinhard, Haisch, Christoph

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2015

Language:

english

File:

PDF, 406 KB

english, 2015

30

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] C108. AIRWAY SMOOTH MUSCLE CELL SIGNALING AND FUNCTION IN HEALTH AND DISEASE - Epac As A Novel Relaxing Factor For Airway Smooth Muscle

Roscioni, Sara S., Maarsingh, Harm, Elzinga, Carolina R.S., Schuur, L Janke, Menzen, Mark H., Halayko, Andrew J., Meurs, Herman, Schmidt, Martina

Year:

2010

Language:

english

File:

PDF, 20 KB

english, 2010

31

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] A62. THE CYTOSKELETON AND CELL CONTRACTILITY - A Role of AKAP5 in PKA and Epac Mediated PKB/Akt Phosphorylation in the Lung.

Bosma, WJ, Menzen, M, Roscioni, SS, Elzinga, CR, Nijholt, IM, Eisel, UL, Halayko, AJ, Meurs, H, Schmidt, M

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

32

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] C18. NOVEL MECHANISMS DRIVING AIRWAY REMODELING IN ASTHMA - Autocrine Wnt5a Signaling Is Increased In Asthma And Regulates TGF-Beta1 Induced ECM Production By Airway Smooth Muscle Cells

Kumawat, Kuldeep, Bos, Sophie, Borger, Peter, Roth, Michael, Tamm, Michael, Postma, Dirkje S., Koppelman, Gerard H., Siedlinski, Matteusz, Halayko, Andrew J., Menzen, Mark H., Baarsma, Hoeke A., Schmi

Year:

2011

Language:

english

File:

PDF, 20 KB

english, 2011

33

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis

Spanjer, Anita I R, Menzen, Mark H, Dijkstra, Akkelies E, van den Berge, Maarten, Boezen, H Marike, Nickle, David C, Sin, Don D, Bossé, Yohan, Brandsma, Corry-Anke, Timens, Wim, Postma, Dirkje S, Meur

Journal:

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

34

Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

Kistemaker, Loes E. M., Bos, I. Sophie T., Menzen, Mark H., Maarsingh, Harm, Meurs, Herman, Gosens, Reinoud

Journal:

Respiratory Research

Year:

2016

Language:

english

File:

PDF, 2.47 MB

english, 2016

35

Noncanonical WNT-5B signaling induces inflammatory responses in human lung fibroblasts

van Dijk, Eline M., Menzen, Mark H., Spanjer, Anita I. R., Middag, Laurens D. C., Brandsma, Corry-Anke A., Gosens, Reinoud

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2016

Language:

english

File:

PDF, 827 KB

english, 2016

36

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D28. DEVELOPMENTAL SIGNALING REBORN IN ADULT LUNG DISEASE - Non-Canonical WNT Signaling Regulates TGF-²1-Induced Extracellular Matrix Production By Airway Smooth Muscle Cells

Kumawat, Kuldeep, Menzen, Mark H., Halayko, Andrew J., Schmidt, Martina, Gosens, Reinoud

Year:

2012

Language:

english

File:

PDF, 20 KB

english, 2012

37

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] C18. NOVEL MECHANISMS DRIVING AIRWAY REMODELING IN ASTHMA - Beta-Catenin Signaling Is Required For TGF-Beta1-Induced Ecm Production By Airway Smooth Muscle

Baarsma, Hoeke A., Menzen, Mark H., Halayko, Andrew J., Meurs, Herman, Kerstjens, Huib, Gosens, Reinoud

Year:

2011

Language:

english

File:

PDF, 20 KB

english, 2011

38

TCD-MONITORING DURING INDUCTION OF ANESTHESIA IN CRITICAL PATIENTS WITH CEREBRAL DISEASES

Schregel, W., Schmieder, K., Menzen, A.

Journal:

Journal of Neurosurgical Anesthesiology

Year:

1997

File:

PDF, 91 KB

1997

39

Selective targeting of CBP/β-catenin inhibits growth of and extracellular matrix remodelling by airway smooth muscle

Koopmans, Tim, Crutzen, Stijn, Menzen, Mark H, Halayko, Andrew J, Hackett, Tillie-Louise, Knight, Darryl A, Gosens, Reinoud

Journal:

British Journal of Pharmacology

Year:

2016

Language:

english

File:

PDF, 965 KB

english, 2016

40

Cooperative signaling by TGF-β1 and WNT-11 drives sm-α-actin expression in smooth muscle via Rho kinase-actin-MRTF-A signaling

Kumawat, Kuldeep, Koopmans, Tim, Menzen, Mark H., Prins, Alita, Smit, Marieke, Halayko, Andrew J., Gosens, Reinoud

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2016

Language:

english

File:

PDF, 5.68 MB

english, 2016

41

Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing

Altmüller, Janine, Haenisch, Britta, Kawalia, Amit, Menzen, Markus, Nöthen, Markus M., Fier, Heide, Molderings, Gerhard J.

Journal:

Year:

2017

Language:

english

File:

PDF, 390 KB

english, 2017

42

Joint Affections in Psoriasis

Journal:

The American Journal of the Medical Sciences

Year:

1905

File:

PDF, 48 KB

1905

43

Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease

Oldenburger, Anouk, Roscioni, Sara S., Jansen, Esther, Menzen, Mark H., Halayko, Andrew J., Timens, Wim, Meurs, Herman, Maarsingh, Harm, Schmidt, Martina, Eickelberg, Oliver

Journal:

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

44

β-Catenin Directs Nuclear Factor-κB p65 Output via CREB-Binding Protein/p300 in Human Airway Smooth Muscle

Koopmans, Tim, Eilers, Roos, Menzen, Mark, Halayko, Andrew, Gosens, Reinoud

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 4.82 MB

english, 2017

45

Elastase-Induced Parenchymal Disruption and Airway Hyper Responsiveness in Mouse Precision Cut Lung Slices: Toward an Ex vivo COPD Model

Van Dijk, Eline M., Culha, Sule, Menzen, Mark H., Bidan, Cécile M., Gosens, Reinoud

Journal:

Frontiers in Physiology

Year:

2017

Language:

english

File:

PDF, 2.58 MB

english, 2017

46

Aspectos fonoaudiológicos em um caso de artrogripose de cabeça e pescoço pediátrico

Trindade, Jennifer Alvares, Freitas, Jordana da Silva, Menzen, Liliane, Laux, Carolina, Barbosa, Lisiane de Rosa, Cardoso, Maria Cristina de Almeida Freitas

Journal:

Year:

2018

Language:

english

File:

PDF, 647 KB

english, 2018

47

Backgrounded Membrane Imaging (BMI) for High-Throughput Characterization of Subvisible Particles During Biopharmaceutical Drug Product Development

Helbig, Constanze, Ammann, Gregor, Menzen, Tim, Friess, Wolfgang, Wuchner, Klaus, Hawe, Andrea

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 2.44 MB

english, 2019

48

Stress Factors in Monoclonal Antibody Drug Substance Production Processes: Critical Assessment of Impact on Product Quality and Control Strategy

Das, Tapan K., Narhi, Linda O., Sreedhara, Alavattam, Menzen, Tim, Grapentin, Christoph, Chou, Danny K., Antochshuk, Valentyn, Filipe, Vasco

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 2.98 MB

english, 2019

49

Intrinsic Differential Scanning Fluorimetry for Fast and Easy Identification of AAV Serotypes

Rieser, Ruth, Penaud-Budloo, Magalie, Bouzelha, Mohammed, Rossi, Axel, Menzen, Tim, Biel, Martin, Büning, Hildegard, Ayuso, Eduard, Winter, Gerhard, Michalakis, Stylianos

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 1.90 MB

english, 2019

50

What makes polysorbate functional? Impact of polysorbate 80 grade and quality on IgG stability during mechanical stress

Grabarek, A.D., Bozic, U., Rousel, J., Menzen, T., Kranz, W., Wuchner, K., Jiskoot, W., Hawe, A.

Journal:

Journal of Pharmaceutical Sciences

Year:

2019

Language:

english

File:

PDF, 14.96 MB

english, 2019

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